Go to Outlook.office.com
Open the setting cog from the top right corner of the website.
Go to the "View all Outlook settings" link in the bottom right of the settings. This allows you to go to Email -> Compose and Reply.
Once created you can assign the signature "For New Messages" and "For Replies/Forwards". To do this you can use the drop down and select the signature you have created.
Any questions please contact [email protected]
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